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. 2022 May 13;133(2):317–326. doi: 10.1002/lary.30152

TABLE III.

Cox Proportional Hazards Multivariable Regression of Overall Survival in Oral Cavity Mucosal Melanoma.

Covariate Total (N = 120) Hazard Ratio (95% CI) p value
Age 1.03 (1.01–1.06) 0.003
Sex
Male 70 1.00 (reference)
Female 50 0.56 (0.33–0.94) 0.03
Race
White 103 1.00 (reference)
Black 11 2.63 (1.14–6.11) 0.02
Asian/Pacific Islander 6 1.55 (0.45–5.22) 0.48
T Stage
T3 70 1.00 (reference)
T4 50 0.95 (0.57–1.82) 0.95
N Stage
N0 82 1.00 (reference)
N1 38 1.94 (1.10–3.42) 0.02
M Stage
M0 115 1.00 (reference)
M1 5 10.13 (3.33–30.86) <0.001
Treatment
Surgery 56 1.00 (reference)
Surgery + RT 48 1.57 (0.88–2.78) 0.12
Surgery + Chemotherapy 4 1.94 (0.54–6.94) 0.31
Surgery + Immunotherapy 5 2.24 (0.48–10.41) 0.31
Surgery + CRT 7 1.09 (0.38–3.19) 0.87
Margins
Negative 98 1.00 (reference)
Positive 22 1.07 (0.56–2.03) 0.85
Neck Dissection (LNY ≥ 18)
No 76 1.00 (reference)
Yes 44 2.23 (1.17–4.24) 0.02
Neck Dissection (LNY ≥ 1)*
No 50 1.00 (reference)
Yes 73 1.54 (0.81–2.93) 0.19

Note: Bold indicates P‐value <0.05.

CI = confidence interval; CRT = chemoradiotherapy; LNY = lymph node yield; RT = radiation therapy.

*

For regression with Neck Dissection (LNY ≥ 1), N = 123;