TABLE 4.

Meta‐analysis for the modified Quigley and Hein Plaque index using a random model

Modified Quigley and Hein Plaque index	Number of comparisons	Comparison	Effect size			Heterogeneity		Online Appendix number
			DiffM	95% CI	p‐Value	I 2	p‐Value	Forrest plot	Funnel plot	TSA
										Number	TSA does research the RIS or not (yes/no)
Grossman et al. (1995) 47 Robinson et al. (1997) 49 Yankell & Emling (1997) 50 Putt et al. (2001) 53 Van der Weijden et al. (2002–1) 54 Goyal et al. (2005) 55 2x Patters et al. (2005) 56 Rosema et al. (2005) 57 Williams et al. (2009) 60 Büchel et al. (2014) 65 Schmickler et al. (2016) 70 2x Schmalz et al. (2017‐AJD) 71 Schmalz et al. (2018‐COI) 73 2x	16	Baseline	−0.03	(−0.08; 0.02)	0.19	0%	0.95	S10A	S10B	NA	NA
		End	0.13	(0.05; 0.21)	<0.001	54%	0.008	S10C	S10D	S10E	Yes
		Difference	?	?	?	?	?	NA	NA	NA	NA

Note: p‐Values are presented in bold if p ≤ 0.05.

Abbreviations: ?, Unclear; NA, Not applicable; RIS, Required Information Size; TSA, Trial sequential analysis.