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. 2022 Jun 25;21(1):77–94. doi: 10.1111/idh.12597

TABLE 10.

Meta‐analysis for the (modified) Gingival index using a random model

(Modified) Gingival index Number of comparisons Comparison Effect size Heterogeneity Online Appendix number
DiffM 95% CI p‐Value I 2 p‐Value Forrest plot Funnel plot TSA
Number TSA does research the RIS or not (yes/no)

Grossman et al. (1995) 47

Yankell & Emling (1997) 50

Putt et al. (2001) 53

Goyal et al. (2009) 59

Williams et al. (2009) 60

Ayad et al. (2012) 61 2x

Klukowska et al. (2012) 62

Klukowska et al. (2013) 63

Klukowska et al. (2014‐12w) 66

Klukowska et al. (2014‐6wCOL) 67

Klukowska et al. (2014‐6wPH) 68

Ccahuana‐Vasquez et al. (2015) 69

Schmickler et al. (2016‐non‐rep) 70 2x

Starke et al. (2017) 72

Schmalz et al. (2018‐COI instr) 73 2x

Ccahuana‐Vasquez et al. (2018) 74

Mirza et al. (2019) 76

Adam et al. (2020) 77

Goyal et al. (2021) 78

22 Baseline 0.00 (−0.00; 0.01) 0.27 0% 0.71 S16A S16B NA NA
End 0.02 (−0.01; 0.05) 0.24 94% <0.00001 S16C S16D S16E Yes

Goyal et al. (2009) 59

Williams et al. (2009) 60

Ayad et al. (2012) 61 2x

Klukowska et al. (2012) 62

Klukowska et al. (2013) 63

Klukowska et al. (2014‐12w) 66

Klukowska et al. (2014‐6wCOL) 67

Klukowska et al. (2014‐6wPH) 68

Ccahuana‐Vasquez et al. (2015) 69

Starke et al. (2017) 72

Ccahuana‐Vasquez et al. (2018) 74

Lv et al. (2018) 75 2x

Mirza et al. (2019) 76

Adam et al. (2020) 77

Goyal et al. (2021) 78

17 Difference 0.00 (−0.04; 0.04) 0.89 97% <0.00001 S16F S16G NA NA

Note: p‐Values are presented in bold if p ≤ 0.05. Interpretation of the heterogeneity: Potentially not important: 0%–40%; Moderate heterogeneity: 40%–60%; Substantial heterogeneity: 60%–80%; Considerable heterogeneity: 80%–100%. According to Sälzer et al. 201531.

Abbreviations: ?, Unclear; NA, Not applicable; RIS, Required Information Size; TSA, Trial sequential analysis.