Table 1.
Variable | ReTUR | No reTUR | P |
---|---|---|---|
Number of patients | 50 | 56 | |
Patient demographics | |||
Age, years, median (IQR) | 74 (70.25–78) | 76 (69–82.25) | 0.43 |
Sex, n (%) | |||
Male | 33 (66) | 43 (77) | 0.28 |
Female | 17 (34) | 13 (23) | |
History of UTUC, n (%) | 6 (12) | 6 (11) | 1 |
Recurrent tumours, n (%) | 6 (12) | 10 (18) | 0.43 |
Positive cytology, n (%) | 14 (28) | 9 (20) | 0.34 |
Multiple tumours, n (%) | 25 (50) | 27 (48) | 1 |
Non‐papillary tumours, n (%) | 8 (16) | 7 (12) | 0.78 |
Sessile tumours, n (%) | 21 (42) | 17 (30) | 0.23 |
Tumour diameter, mm, mean (SD) | 20.6 (9.7) | 20.8 (10.9) | 0.93 |
Number of tumours, mean (SD) | 2.22 (2.26) | 2.16 (1.91) | 0.88 |
Pathological diagnosis at initial ERBT | |||
Concomitant CIS, n (%) | 22 (44) | 15 (27) | 0.07 |
Adequate sampling of MP, n (%) | 47 (94) | 52 (93) | 1 |
pT1a/b sub‐staging, n (%) | |||
pT1a | 36 (72) | 38 (68) | 0.68 |
pT1b | 14 (28) | 18 (32) | |
Positive horizontal margin, n (%) | 21 (42) | 15 (37) | 0.52 |
Positive vertical margin, n (%) | 4 (8) | 3 (5.4) | 1 |
Pathological diagnosis at repeat resection | |||
Residual pTa/is | 6 (12) | ‐ | |
Residual pT1 | 3 (6) | ‐ | |
Upstaging to pT2 | 0 | ‐ | |
Treatment and oncological outcomes | |||
Immediate bladder instillation therapy, n (%) | 33 (66) | 42 (75) | 0.39 |
Maintenance bladder instillation therapy, n (%) | 36 (72) | 30 (54) | 0.07 |
Follow‐up, months, median (IQR) | 23 (13–35) | 22.5 (11.75–42.25) | 0.79 |
Recurrence, n (%) | 18 (36) | 18 (32) | 0.68 |
Progression, n (%) | 7 (14) | 6 (11) | 0.77 |
2‐year RFS, % (95% CI) | 55.1 (37.2–69.8) | 59.9 (43.1–73.2) | 0.55 |
3‐year PFS, % (95% CI) | 80.6 (59.5–91.4) | 82.6 (63.7–92.2) | 0.64 |
UTUC, upper urinary tract urothelial carcinoma.