TABLE 5.
Hematologic laboratory abnormalities by age group: ≥70 and <70 years, safety population
| ≥70 Years (n = 85) | <70 Years (n = 214) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Isa‐Kd (n = 51) | Kd (n = 34) | Isa‐Kd (n = 126) | Kd (n = 88) | |||||||||
| Grade (G) | ||||||||||||
| Laboratory parameter, n (%) | Any | G3 | G4 | Any | G3 | G4 | Any | G3 | G4 | Any | G3 | G4 |
| Anemia | 51 (100) | 9 (17.6) | 0 | 33 (97.1) | 7 (20.6) | 0 | 125 (99.2) | 30 (23.8) | 0 | 88 (100) | 17 (19.3) | 0 |
| Thrombo‐cytopenia | 48 (94.1) | 11 (21.6) | 0 | 28 (82.4) | 7 (20.6) | 1 (2.9) | 119 (94.4) | 22 (17.5) | 20 (15.9) | 79 (89.8) | 12 (13.6) | 9 (10.2) |
| Neutropenia | 28 (54.9) | 8 (15.7) | 0 | 5 (14.7) | 1 (2.9) | 0 | 69 (54.8) | 23 (18.3) | 3 (2.4) | 48 (54.5) | 7 (8.0) | 1 (1.1) |
Abbreviations: d, dexamethasone; Isa, isatuximab; K, carfilzomib.