Table 4.
Cutoff Values for B‐Mode Ratio to Rule‐In and Rule‐Out Steatosis in a Cohort of 137 Patients With ALD and NAFLD
| Cutoff Value | Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | PPV (%) (95% CI) | NPV (%) (95% CI) | Correctly Classified (%) | |
|---|---|---|---|---|---|---|
| ≥S1 | ||||||
| Optimal | 1.46 | 48 (38–59) | 100 (88–100) | 100 (92–100) | 37 (26–49) | 60 |
| Rule‐out | 1.09 | 91 (84–96) | 43 (25–63) | 85 (76–91) | 60 (36–81) | 80 |
| Rule‐in | 1.45 | 51 (40–61) | 96 (82–100) | 98 (89–100) | 37 (26–49) | 61 |
| ≥S2 | ||||||
| Optimal | 1.48 | 64 (49–77) | 85 (74–92) | 74 (59–87) | 77 (66–86) | 76 |
| Rule‐out | 1.21 | 90 (78–97) | 44 (32–56) | 53 (42–64) | 86 (71–95) | 63 |
| Rule‐in | 1.67 | 38 (25–53) | 90 (81–96) | 73 (52–88) | 67 (57–77) | 69 |
| =S3 | ||||||
| Optimal | 1.39 | 86 (65–97) | 60 (49–69) | 32 (21–46) | 95 (87–99) | 64 |
| Rule‐out | 1.34 | 91 (71–99) | 55 (44–65) | 31 (20–43) | 96 (88–100) | 61 |
| Rule‐in | 1.92 | 18 (5–40) | 91 (83–96) | 31 (9–61) | 83 (75–90) | 78 |
Optimal cutoff by Youden Index. Rule‐out and rule‐in cutoff chosen based on sensitivity and specificity above 90% respectively.