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5FC dosage adjustment with renal dysfunction.
| GFR (ml/min) and 5FC dose adjustment | ||
|---|---|---|
| 20–40 | 10–20 | Less than 10 |
| 50 mg/kg 12 hourly | 50 mg/kg 24 hourly | 50 mg/kg then dose according to levels. Dose of 0.5–1 g daily is usually adequate |
5FC, 5-fluorocytosine; GFR, Glomerular filtration rate.
