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. 2023 Apr 10;23:236. doi: 10.1186/s12884-023-05525-5

Table 3.

Ultrasonographic characteristics and pregnancy outcome of 26 UPSVS fetuses

No. Type of UPSVS Complicated cardiac anomalies CVPS scoring Complicated extracardiac anomalies Karyotype and CNV-Seq Fetal outcomes
1 I - 5 SUA - Terminated
2 I - 7 - N/A Terminated
3 I - 6 - N/A Terminated
4 I VSD 5 CDH N/A Terminated
5 II ARSA 9 - 47,XN,+21 Terminated
6 II - 10 - 47,XY,+21 Terminated
7 II VSD 9 FGR, ANB 47,XN,+21 Terminated
8 II - 10 - - Term birth
9 II - 10 - - Term birth
10 II - 10 - - Term birth
11 II - 5 - 47,XN,+21 Stillbirth
12 II - 10 TRAPs - Terminated
13 II - 6 AHP N/A Terminated
14 II - 10 - - Term birth
15 IIIA TGA, RAOA 10 RPD, HN, SUA N/A Terminated
16 IIIA - 10 R-MCDK - Terminated
17 IIIA - 6 - - Terminated
18 IIIB - 4 FGR, ANB 47,XN,+3(8)/46,XN(44) Terminated
19 IIIB - 10 - N/A Term birth
20 IIIB - 10 SUA 46,XX,del(10)(q26.37) Terminated
21 IIIB - 10 - - Stillbirth
22 IIIB - 10 - 46,XY,dup(8)(p23.1) Terminated
23 IIIB - 5 FE N/A Terminated
24 IIIB - 8 AHP, CPC 47,XY,+18 Terminated
25 IIIB VSD 9 CPC 47,XY,+18 Terminated
26 IIIB - 10 - N/A Term birth

“-”: normal test/ ultrasonographic result

N/A: Karyotype and CNV-Seq were not performed

VSD: ventricular septal defect; CDH: congenital diaphragmatic hernia; ARSA: aberrant right subclavian artery; TGA: complete transposition of great arteries; RAOA: right aortic arch; SUA: single umbilical artery; CPC: choroid plexus cyst; RPD: right pulmonary agenesis or dysplasia; HN: hydronephrosis; ANB: absent nasal bone; FE: fetal edema; AHP: abnormal hand posture; TRAPs: twin reversed arterial perfusion sequence; R-MCDK: right polycystic dysplasia kidney; FGR: fetal growth restriction