Table 1.
Baseline characteristics of the cohort before and after PSM
| Variables | Before PSM (n = 170) | After PSM (n = 105) | ||||||
|---|---|---|---|---|---|---|---|---|
| All (n = 170) | LLR (n = 127) | OLR (n = 43) | p-value | All (n = 105) | LLR (n = 70) | OLR (n = 35) | p-value | |
| Age, median (IQR), year | 65 (59–70) | 65 (58–70) | 66 (60–73) | 0.533 | 66 (59–71) | 66 (58–71) | 66 (59–73) | 0.721 |
| Male, n (%) | 81 (47.6) | 60 (47.2) | 21 (48.8) | 0.857 | 52 (49.5) | 35 (50.0) | 17 (48.6) | 0.890 |
| BMI, median (IQR) (kg/m2) | 22.2 (20.7–24.6) | 22.6 (20.8–24.8) | 21.9 (20.1–24.4) | 0.299 | 22.6 (20.8–24.7) | 23.0 (20.9–25.3) | 21.8 (20.1–24.5) | 0.172 |
| Cirrhosis, n (%) | 24 (14.1) | 18 (14.2) | 6 (14.0) | 0.972 | 14 (13.3) | 8 (11.4) | 6 (17.1) | 0.417 |
| Hepatitis B, n (%) | 31 (18.2) | 22 (17.3) | 9 (20.9) | 0.597 | 18 (17.1) | 10 (14.3) | 8 (22.9) | 0.272 |
| ASA score, n (%) | 0.105 | 0.333 | ||||||
| I | 1 (0.6) | 1 (0.7) | 0 (0) | 1 (1.0) | 1 (1.4) | 0 (0) | ||
| II | 160 (94.1) | 117 (92.1) | 43 (100) | 100 (95.2) | 65 (92.9) | 35 (100) | ||
| III | 9 (5.3) | 9 (7.0) | 0 (0) | 4 (3.8) | 4 (5.7) | 0 (0) | ||
| TBIL > 26 µmol/L, n (%) | 25 (15.0) | 13 (10.5) | 12 (27.9) | 0.006 | 15 (14.3) | 10 (14.3) | 5 (14.3) | 0.955 |
| ALB < 40 g/L, n (%) | 80 (47.9) | 57 (46) | 23 (53.5) | 0.395 | 51 (48.6) | 34 (48.6) | 17 (48.6) | 1.000 |
| PT > 14.5 s, n (%) | 20 (11.7) | 15 (12.2) | 5 (11.6) | 0.974 | 10 (9.5) | 7 (10.0) | 3 (8.6) | 0.814 |
| PLT < 125 × 10^9/L | 30 (17.6) | 20 (15.7) | 10 (23.3) | 0.264 | 20 (19.0) | 11 (15.7) | 9 (25.7) | 0.219 |
| AFP > 8.78 ng/ml, n (%) | 11 (6.7) | 7 (5.7) | 4 (9.8) | 0.368 | 8 (7.6) | 5 (7.1) | 3 (8.6) | 0.795 |
| CEA > 5 ng/ml, n (%) | 49 (29.9) | 37 (30.1) | 12 (29.3) | 0.922 | 31 (29.5) | 24 (34.3) | 7 (20.0) | 0.130 |
| CA19-9 > 37 IU/ml, n (%) | 107 (65.6) | 77 (63.1) | 30 (73.2) | 0.241 | 62 (59.0) | 40 (57.1) | 22 (62.9) | 0.575 |
| CA12-5 > 35 U/ml, n (%) | 42 (27.3) | 28 (24.3) | 14 (35.9) | 0.162 | 35 (33.3) | 23 (32.9) | 12 (34.3) | 0.884 |
| Child–Pugh, n (%) | 0.001 | 0.631 | ||||||
| A | 155 (91.2) | 121 (96.9) | 34 (79.1) | 102 (97.1) | 68 (97.1) | 34 (97.1) | ||
| B | 15 (8.8) | 6 (3.1) | 9 (20.9) | 3 (2.9) | 2 (2.8) | 1 (2.8) | ||
| C | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
| Anatomical liver resection, n (%) | 131 (77.0) | 100 (78.7) | 31 (72.1) | 0.370 | 79 (75.2) | 55 (78.6) | 24 (68.6) | 0.263 |
| Extent of resection, n (%) | 0.322 | 0.571 | ||||||
| Local/wedge excision | 26 (15.3) | 15 (11.8) | 11 (25.5) | 0.030 | 20 (19.0) | 10 (14.3) | 10 (28.6) | 0.332 |
| Segmentectomy | 31 (18.2) | 22 (17.3) | 9 (20.9) | 0.596 | 18 (17.1) | 12 (17.1) | 6 (17.1) | 1.000 |
| Hemihepatectomy | 84 (49.4) | 69 (54.3) | 15 (34.8) | 0.027 | 50 (47.6) | 38 (54.3) | 12 (34.3) | 0.053 |
| Extended hemihepatectomy | 28 (16.5) | 21 (16.5) | 7 (16.2) | 0.968 | 16 (15.2) | 10 (14.3) | 6 (17.1) | 0.701 |
| NA | 1 (0.6) | 0 (0) | 1 (2.3) | 0.085 | 1 (1.0) | 0 (0) | 1 (2.9) | 0.155 |
| Major sizes, median (IQR), cm | 4.8 (3.5–6.5) | 4.5 (3.5–6.0) | 5.4 (3.1–7.5) | 0.283 | 5.0 (3.7–6.5) | 4.6 (3.9–6.1) | 5.4 (3.1–7.5) | 0.441 |
| Multiple tumors, n (%) | 31 (18.2) | 21 (16.5) | 10 (23.3) | 0.323 | 13 (12.4) | 7 (10.0) | 6 (17.1) | 0.295 |