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. Author manuscript; available in PMC: 2023 Apr 10.
Published in final edited form as: Nat Genet. 2022 Aug 4;54(11):1664–1674. doi: 10.1038/s41588-022-01140-w

ED Fig 3. Candidate driver alterations discovered in IGHV subtypes.

ED Fig 3.

a-b. Landscape of putative driver genes and sCNAs in M-CLL (a, n=512) and U-CLL (b, n=459) with associated frequencies (rows, barplots). Header tracks annotate cohort, IGHV status (purple, M-CLL; orange, U-CLL), disease type (blue, CLL; yellow, MBL), epitype (blue, n-CLL; yellow, i-CLL; red, m-CLL), datatype (white, WES; yellow, WGS; blue, both); prior treatment, U1 and IGLV3–21R110 mutations are annotated in black; magenta label - novel alterations; asterisks - discovery by CLUMPS.