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. 2023 Mar 29;19(3):e1011290. doi: 10.1371/journal.ppat.1011290

Fig 3. SIV infection enhances SOD1 production in the frontal cortex in the brain.

Fig 3

(A) Representative images of frontal cortex tissue of SIV infected (acute, chronic or virally suppressed [VS]) or uninfected controls was stained using fluorescent multiplex immunohistochemistry to detect GFAP (astrocyte), SOD1 and DAPI (4′,6-diamidino-2-phenylindole). Images shown at x30 magnification; scale bars: 50μm and 25μm (single channel inset). (B) Frequency of total SOD1+ cells or (C) SOD1+ astrocytes in frontal tissue. Comparisons made using Mann-Whitney U test, *P<0.05, **P<0.01, ***P<0.001). Median and interquartile ranges shown.