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. 2023 Mar 29;19(3):e1011290. doi: 10.1371/journal.ppat.1011290

Fig 6. SIV RNA, type I interferon responses and barrier damage in the gut are associated with immune activation in the frontal cortex of virally suppressed SIV+ animals.

Fig 6

Correlative analysis of levels of immune activation markers in white matter (WM) or grey matter (GM) from frontal cortex tissue of virally suppressed SIV+ animals (n = 7–10), as determined by IHC, to levels of (A) SIV viral RNA, (B and C) Mx1, (D) pSTAT1 or (E and F) myeloperoxidase (MPO)+ cells from matched gut tissue. Parameters were log transformed. Spearman rho and P values shown. P<0.05 considered statistically significant.