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. 2023 Apr 10;19(4):e1010986. doi: 10.1371/journal.pcbi.1010986

Fig 4. Distinct EEG signatures from reduced SST vs PV interneuron inhibition.

Fig 4

(a) Power spectral density plot of simulated EEG from the healthy (black) and reduced SST interneuron inhibition (depression, red) microcircuit models, with high-low opacity indicating a 20%, 40% and 60% reduction in inhibition (n = 30 randomized microcircuits per condition, bootstrapped mean). (b) Fitted aperiodic component of the PSD. (c) Fitted periodic component of the PSD. (d-f) Same as (a-c) but for microcircuits with reduced PV interneuron inhibition.