Table 1. Clinicopathologic parameters and the expression of GATA family members in KIRC.
Characteristics | N | GATA1 | GATA2 | GATA3 | GATA4 | GATA5 | GATA6 | ||||||||||||
Low | High | P | Low | High | P | Low | High | P | Low | High | P | Low | High | P | Low | High | P | ||
Gender | |||||||||||||||||||
Male | 337 | 229 | 108 | 0.071 | 203 | 134 | 0.416 | 268 | 69 | 0.127 | 321 | 16 | 0.689 | 251 | 86 | 0.023 | 217 | 120 | 0.157 |
Female | 180 | 136 | 44 | 115 | 65 | 153 | 27 | 170 | 10 | 117 | 63 | 127 | 53 | ||||||
Age (year) | |||||||||||||||||||
≤60 | 258 | 186 | 72 | 0.457 | 148 | 110 | 0.053 | 217 | 41 | 0.118 | 247 | 11 | 0.427 | 183 | 74 | 0.900 | 174 | 84 | 0.664 |
>60 | 259 | 179 | 80 | 170 | 89 | 204 | 55 | 244 | 15 | 185 | 75 | 170 | 89 | ||||||
T stage | |||||||||||||||||||
T1 + T2 | 331 | 233 | 98 | 0.890 | 187 | 144 | 0.002 | 279 | 52 | 0.026 | 322 | 9 | 0.001 | 227 | 104 | 0.082 | 237 | 46 | 0.000 |
T3 + T4 | 186 | 132 | 54 | 131 | 55 | 142 | 44 | 169 | 17 | 141 | 45 | 107 | 127 | ||||||
N stage | |||||||||||||||||||
Nx | 268 | 189 | 79 | 0.863 | 149 | 119 | 0.011 | 214 | 54 | 0.111 | 255 | 13 | 0.274 | 177 | 91 | 0.025 | 178 | 90 | 0.041 |
N0 | 235 | 167 | 68 | 158 | 77 | 198 | 37 | 224 | 11 | 181 | 54 | 161 | 74 | ||||||
N1 | 14 | 9 | 5 | 11 | 3 | 9 | 5 | 12 | 2 | 10 | 4 | 5 | 9 | ||||||
M stage | |||||||||||||||||||
Mx | 28 | 22 | 6 | 0.352 | 16 | 12 | 0.001 | 25 | 3 | 0.807 | 26 | 2 | 0.262 | 14 | 14 | 0.005 | 17 | 11 | 0.185 |
M0 | 412 | 285 | 127 | 240 | 172 | 336 | 76 | 393 | 19 | 291 | 121 | 282 | 130 | ||||||
M1 | 77 | 58 | 19 | 62 | 15 | 60 | 17 | 72 | 5 | 63 | 14 | 45 | 32 | ||||||
Pathologic stage | |||||||||||||||||||
Stage I + II | 313 | 216 | 97 | 0.326 | 173 | 140 | 0.000 | 266 | 47 | 0.010 | 305 | 8 | 0.001 | 215 | 98 | 0.122 | 225 | 88 | 0.001 |
Stage III + IV | 204 | 149 | 55 | 145 | 59 | 155 | 49 | 186 | 18 | 153 | 51 | 119 | 85 | ||||||
Histologic grade | |||||||||||||||||||
grade 1 + 2 | 238 | 161 | 77 | 0.174 | 123 | 115 | 0.000 | 196 | 42 | 0.619 | 235 | 3 | 0.000 | 155 | 83 | 0.005 | 172 | 66 | 0.011 |
grade 3 + 4 | 279 | 204 | 75 | 195 | 84 | 225 | 54 | 256 | 23 | 213 | 66 | 172 | 107 |
Bold font indicates significant difference.