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. 2023 Mar 23;15(6):2170–2188. doi: 10.18632/aging.204607

Table 1. Clinicopathologic parameters and the expression of GATA family members in KIRC.

Characteristics N GATA1 GATA2 GATA3 GATA4 GATA5 GATA6
Low High P Low High P Low High P Low High P Low High P Low High P
Gender
Male 337 229 108 0.071 203 134 0.416 268 69 0.127 321 16 0.689 251 86 0.023 217 120 0.157
Female 180 136 44 115 65 153 27 170 10 117 63 127 53
Age (year)
≤60 258 186 72 0.457 148 110 0.053 217 41 0.118 247 11 0.427 183 74 0.900 174 84 0.664
>60 259 179 80 170 89 204 55 244 15 185 75 170 89
T stage
T1 + T2 331 233 98 0.890 187 144 0.002 279 52 0.026 322 9 0.001 227 104 0.082 237 46 0.000
T3 + T4 186 132 54 131 55 142 44 169 17 141 45 107 127
N stage
Nx 268 189 79 0.863 149 119 0.011 214 54 0.111 255 13 0.274 177 91 0.025 178 90 0.041
N0 235 167 68 158 77 198 37 224 11 181 54 161 74
N1 14 9 5 11 3 9 5 12 2 10 4 5 9
M stage
Mx 28 22 6 0.352 16 12 0.001 25 3 0.807 26 2 0.262 14 14 0.005 17 11 0.185
M0 412 285 127 240 172 336 76 393 19 291 121 282 130
M1 77 58 19 62 15 60 17 72 5 63 14 45 32
Pathologic stage
Stage I + II 313 216 97 0.326 173 140 0.000 266 47 0.010 305 8 0.001 215 98 0.122 225 88 0.001
Stage III + IV 204 149 55 145 59 155 49 186 18 153 51 119 85
Histologic grade
grade 1 + 2 238 161 77 0.174 123 115 0.000 196 42 0.619 235 3 0.000 155 83 0.005 172 66 0.011
grade 3 + 4 279 204 75 195 84 225 54 256 23 213 66 172 107

Bold font indicates significant difference.