Table 1.

Summary of the zmm suppressor screen results

		Number of alleles identified in each screen
		total	zip4	hei10	msh5	shoc1	msh4 (Ler)
	Number of M2 populations screened	∼7000	∼2000	∼2000	∼1000	∼1000	∼1000
identified gene	FANCC	1					1
	FANCM	29	5	5	4	8	7
	MHF2	4	1	2			1
	TOP3	4		3			1
	RECQ4	3					3
	RMI1	2				1	1
	FIGL1	15	2	5	3	3	2
	FLIP	1		1
	total	59	8	16	7	12	16

A suppressor screen was performed in five zmm mutants (zip4, hei10, msh5, shoc1 and msh4). One to two thousand independent M2 populations were screened for each zmm. At total of 59 causal mutations falling in eight genes were identified and we report the number of alleles identified per gene and per screen. The colors represent three distinct pathways (FA blue, BTR green, FIGL1 red). Note that msh4 is in the Ler background while others are in Col. As RECQ4 is duplicated in Col but not in Ler, it could be found only in the msh4 screen. The list of mutant alleles is shown in Supplementary Table S2.