Fig. 7.

Effects of chronic restraint stress (CRS) on pyramidal neurons in the mPFC. A) Schematic drawing of the experimental timeline. B, C, and D) Effects of CRS on pushing, advancing, and retreat behaviors of the control and CRS groups, respectively. E) Comparison of the spontaneous discharge signals of representative pyramidal neurons in the control and CRS groups. F) Effects of CRS on the firing rates of pyramidal neurons. G) Effects of CRS on the inter-spike intervals of pyramidal neurons. **p < 0.01, compared with control mice, n = 10–12 per group.