TABLE 3.
Hazard ratios (95% CI) for all‐cause mortality by DBP levels stratified by selected covariates in participants with SBP less than 130 mmHg.
| DBP, mmHg | ||||||
|---|---|---|---|---|---|---|
| Variables | No anti‐hypertension drug | Anti‐hypertension drug | ||||
| <60 | 60 to <70 | 70 to <80 | <60 | 60 to <70 | 70 to <80 | |
| Population | ||||||
| All | 1.46 (1.21–1.75) | 1.10 (0.91–1.31) | ref | 0.99 (0.73–1.36) | 0.79 (0.57–1.11) | 0.88 (0.64–1.22) |
| SBP <120 mmHg | 1.39 (1.11–1.73) | 0.90 (0.73–1.10) | ref | 0.79 (0.53–1.18) | 0.61 (0.40–0.94) | 0.74 (0.49–1.14) |
| Age, yrs | ||||||
| <70 | 1.68 (1.35–2.08) | 1.13 (0.88–1.44) | ref | 1.25 (0.84–1.85) | 0.94 (0.62–1.42) | 0.94 (0.61–1.44) |
| ≥70 | 1.46 (1.14–1.86) | 1.03 (0.83–1.28) | ref | 1.04 (0.71–1.52) | 0.88 (0.58–1.33) | 0.88 (0.58–1.34) |
| Smoking | ||||||
| Current | 1.29 (0.94–1.78) | 1.17 (0.88–1.56) | ref | 0.86 (0.49–1.51) | 0.60 (0.33–1.08) | 0.93 (0.55–1.55) |
| Others | 1.29 (0.78–2.13) | 0.97 (0.55–1.72) | ref | 1.52 (0.76–3.05) | 1.64 (0.79–3.43) | 1.91 (0.90–4.03) |
| Myocardial infarction | ||||||
| Yes | 1.49 (1.23–1.79) | 1.11 (0.91–1.35) | ref | 0.99 (0.71–1.38) | 0.76 (0.53–1.10) | 0.84 (0.60–1.19) |
| No | 1.04 (0.59–1.84) | 0.82 (0.45–1.50) | ref | 0.70 (0.30–1.63) | 0.30 (0.13–0.68) | 0.77 (0.34–1.74) |
| Stroke | ||||||
| Yes | 1.48 (1.22–1.79) | 1.12 (0.93–1.34) | ref | 1.00 (0.71–1.40) | 0.94 (0.67–1.33) | 0.87 (0.62–1.23) |
| No | 1.04 (0.59–1.84) | 0.88 (0.46–1.69) | ref | 0.98 (0.47–2.02) | 1.00 (0.50–1.99) | 0.90 (0.42–1.97) |
| Heart failure | ||||||
| Yes | 1.47 (1.21–1.77) | 1.11 (0.92–1.35) | ref | 1.06 (0.76–1.46) | 0.85 (0.60–1.20) | 0.91 (0.64–1.29) |
| No | 1.81 (0.71–4.64) | 0.69 (0.34–1.39) | ref | 0.99 (0.38–2.59) | 1.09 (0.41–2.93) | 1.59 (0.63–4.00) |
| Chronic kidney disease | ||||||
| Yes | 1.44 (1.20–1.73) | 1.11 (0.92–1.33) | ref | 0.98 (0.71–1.37) | 0.78 (0.55–1.10) | 0.85 (0.62–1.18) |
| No | 1.73 (1.19–2.52) | 1.09 (0.69–1.73) | ref | 0.88 (0.52–1.50) | 0.73 (0.42–1.25) | 0.72 (0.40–1.30) |
| Diabetes | ||||||
| Yes | 1.38 (1.12–1.70) | 1.09 (0.90–1.32) | ref | 1.06 (0.76–1.49) | 0.80 (0.55–1.18) | 0.90 (0.64–1.27) |
| No | 1.67 (1.07–2.61) | 1.16 (0.80–1.68) | ref | 1.28 (0.73–2.23) | 0.99 (0.51–1.92) | 1.21 (0.67–2.19) |
| Cancer | ||||||
| Yes | 1.44 (1.17–1.76) | 1.10 (0.89–1.35) | ref | 0.93 (0.64–1.35) | 0.74 (0.51–1.06) | 0.76 (0.54–1.06) |
| No | 1.39 (1.11–1.73) | 0.90 (0.73–1.10) | ref | 0.79 (0.53–1.18) | 0.61 (0.40–0.94) | 0.74 (0.49–1.14) |
Abbreviation: DBP, diastolic blood pressure.