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. 2023 Feb 23;41(5):547–559. doi: 10.1007/s40273-022-01219-6

Table 4.

Excess annual healthcare costs (£) associated with cardiovascular and non-vascular events

Event (reference: no) Participants without previous CVD Participants with previous CVD
Primary care cost (95% CI) Hospital care cost (95% CI) Primary care cost (95% CI) Hospital care cost (95% CI)
Cardiovascular events
Myocardial infarction
 Same year 190 (150–240) 4340 (4050–4640) 230 (130–340) 5610 (5170–6040)
 1 year ago a 370 (280–450) a 710 (460–970)
 2 years ago a 190 (120–260) a 370 (240–500)
 ≥ 3 years ago a 160 (100–220) a a
Stroke
 Same year 360 (250–470) 5590 (5340–5840) 430 (270–590) 6170 (5780–6560)
 1 year ago a 1060 (870–1240) a 1180 (940–1430)
 2 years ago a 410 (330–500) a 810 (610–1010)
 ≥ 3 years ago a 310 (240–390) a a
Coronary revascularization
 Same year 390 (310–470) 7140 (6920–7360) 230 (170–300) 7200 (6920–7490)
 1 year ago 70 (40–100) 210 (160–270) 10 (−40 to 60) 480 (330–630)
 2 years ago a 170 (120–220) a 160 (80–250)
 ≥ 3 years ago a 120 (80–170) a a
 Vascular death −100 (−150 to −40) 1560 (1240–1880) −20 (−190 to 160) 2720 (2280–3160)
Non-vascular events
Diabetes
 < 10 years ago 360 (340–380) 160 (140–170) 340 (300–390) 310 (260–370)
 ≥ 10 years ago 560 (520–600) 90 (60–110) 570 (490–650) 240 (190–300)
Cancer
 Same year 360 (340–380) 6150 (6050–6250) 240 (190–290) 6240 (5970–6520)
 1 year ago a 2970 (2890–3060) a 2740 (2520–2950)
 2 years ago a 1160 (1100–1230) a 1340 (1170–1510)
 3 years ago a 850 (800–900) a 1090 (930–1250)
 4 years ago a 670 (620–720) a 750 (670–840)
 ≥ 5, < 10 years ago 160 (130–180) 410 (400–430) 120 (70–180) 600 (540–660)
 ≥ 10 years ago 80 (70–90) a a a
Non-vascular death 390 (320–460) 5350 (5130–5560) 200 (70–330) 6040 (5630–6460)

Estimates adjusted for patient sociodemographic and clinical characteristics and rounded to UK£10

CI confidence interval, CVD cardiovascular disease, MI myocardial infarction

aExcess annual cost remains as in preceding annual period (e.g. £190 excess annual primary care costs in each year following MI)