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. 2023 Mar 4;62(4):587–598. doi: 10.1007/s40262-023-01210-0

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 3 — Kaplan–Meier plot for progression-free survival by average exposure tertile. Data derived from 98 patients with at least one measurable cabozantinib concentration, a valid baseline tumor assessment, and at least one evaluable post-baseline tumor assessment in COSMIC-311. Dashed lines represent 95% confidence intervals for each exposure tertile. CAVG0T predicted average cabozantinib concentration from time zero to the event or censoring time, PFS progression-free survival