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. 2023 Apr 10;13:5822. doi: 10.1038/s41598-023-33021-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Visualization using GradCAM. (A) Visualization using Gradient-weighted class activation mapping (GradCAM) in a “breakup positive” frame. The raw image and GradCAM image with heatmap guidance. The black spots that display the breakup area are emphasized by the heatmap in the "raw image + GradCAM". (B) Visualization using GradCAM in a “breakup negative” frame. The raw image and GradCAM image with heatmap guidance. No emphasis on the cornea.