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. 2023 Apr 10;13:5846. doi: 10.1038/s41598-023-31959-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The protein expression of TAF15 is upregulated in GC. (a,b) Western blot analysis for the expression of TAF15 in GC cell lines (MKN28, AGS, MKN45, HGC27) and GES-1 (Human Gastric mucosal Epithelial Cell). p values were calculated by One-way ANOVA. The experiment was repeated three times. (c,d) Western blot analysis for the expression of TAF15 in 24 GC tissues (T) and matched adjacent normal tissues (N). p values were calculated by student-t test. Three replicate experiments were performed. (e) Immunohistochemistry analysis for the expression of TAF15 in 131 GC samples and 24 adjacent normal samples. Representative images are shown. TFA15 staining was mostly detected in cell nucleus, and TFA15 was highly expressed in GC tissues. (f) The combined staining score of TAF15 in tumor tissues comparing with adjacent normal tissues. p values were calculated by student-t test. *p < 0.05, ***p < 0.001, ****p < 0.0001.