Figure 3.

Representative caudal section of a pleomorphic sarcoma (patient 2). Color-coded landmarks were defined by a pathologist and radiologist on (A) in vivo MRI, (B) ex vivo MRI, the specimen (not shown), and (C) the H&E microtomy section. (D) Exemplary illustration of the TRE computation: landmarks were randomly split into two sets, one for nonrigid co-registration (green) and the other for evaluating the co-registration accuracy as the Euclidian distance in millimeters (white connections of landmarks). TRE: target registration error