Table 2.
Logistic regression analysis of RRM2 expression association with clinical pathological characteristics.
| Characteristics | Total (N) | Odds Ratio (OR) | P value |
|---|---|---|---|
| T stage (T1&T2 vs. T3&T4) | 371 | 1.698 (1.057-2.753) | 0.030 |
| N stage (N0 vs. N1) | 258 | 2.522 (0.318-51.354) | 0.426 |
| M stage (M0 vs. M1) | 272 | 0.291 (0.014-2.308) | 0.288 |
| Pathologic stage (Stage I &Stage II vs. Stage III &Stage IV) | 350 | 1.723 (1.063-2.821) | 0.029 |
| Tumor status (With tumor vs. Tumor free) | 355 | 1.640 (1.076-2.511) | 0.022 |
| Gender (Male vs. Female) | 374 | 0.764 (0.494-1.179) | 0.225 |
| Age (>60 vs. ≤60) | 373 | 0.629 (0.417-0.946) | 0.026 |
| Residual tumor (R0 vs. R1&R2) | 345 | 1.044 (0.398-2.738) | 0.930 |
| Histologic grade (G1&G2 vs. G3&G4) | 369 | 2.893 (1.870-4.524) | <0.001 |
| AFP (ng/ml) (>400 vs. ≤400) | 280 | 3.768 (2.084-7.065) | <0.001 |
| Adjacent hepatic tissue inflammation (None vs. Mild &Severe) | 237 | 1.207 (0.724-2.016) | 0.471 |
| Child-Pugh grade (A vs. B&C) | 241 | 1.402 (0.581-3.452) | 0.452 |
| Vascular invasion (NO vs. YES) | 318 | 1.403 (0.883-2.236) | 0.152 |