. 2023 Mar 28;14:1150803. doi: 10.3389/fimmu.2023.1150803

Table 2.

The association between the percentages of CD226⁺ cells, CD226⁺ cells in the epithelial cell region, and CD226⁺ cells in the stromal cell region in tumor and clinical features of GC patients.

Clinical parameters	cases	CD226⁺ cells infiltration		OR	χ ²	P-value	CD226⁺ cells infiltration		OR	χ ²	P-value	CD226⁺ cells infiltration		OR	χ ²	P-value
Clinical parameters	cases	Low	High	OR	χ ²	P-value	Low	High	OR	χ ²	P-value	Low	High	OR	χ ²	P-value
Gender
Male	64	37	27	1.542	1.034	0.309	48	16	1.435	0.601	0.438	46	18	1.065	0.018	0.893
Female	34	16	18				23	11				24	10
Age (years)
<66	50	23	27	0.499	2.803	0.094	32	18	0.432	3.201	0.074	30	20	0.316	5.928	0.015
≥66	46	29	17				37	9				38	8
Tumor size (cm)
<5.5	48	23	25	0.603	1.510	0.219	34	14	0.810	0.211	0.646	31	17	0.480	2.525	0.112
≥5.5	48	29	19				36	12				38	10
T stage
T_1-2	15	7	8	0.719	0.344	0.558	10	5	0.733	0.267	0.605	11	4	1.138	0.011	0.916
T_3-4	82	45	37				60	22				58	24
N stage
N₀	27	15	12	1.053	0.013	0.910	18	9	0.642	0.813	0.367	20	7	1.143	0.068	0.794
N_1-3	70	38	32				53	17				50	20
M stage
M₀	89	46	43	0.153	2.491	0.115	64	25	0.366	0.288	0.591	62	27	0.328	0.435	0.510
M₁	8	7	1				7	1				7	1
Pathological stage
II+III	87	48	39	1.477	0.371	0.542	62	25	0.551	0.144	0.704	62	25	0.930	0.064	0.800
IV	11	5	6				9	2				8	3
TNM
I+II	41	22	19	0.896	0.070	0.792	28	13	0.601	1.193	0.275	32	9	1.730	1.349	0.245
III+IV	55	31	24				43	12				37	18

The values of cutoff point were 3.683 (in total region), 0.053 (in epithelial region), 0.070 (in stromal region). Values higher than the cutoff point were defined as “High”, and others were defined as “Low”. Bold signifies P<0.05.