. 2023 Mar 28;14:1150803. doi: 10.3389/fimmu.2023.1150803

Table 5.

The association between the percentages of CD226⁺CD8⁺IFN-γ⁺T cells/CD8⁺CD226⁺T cells, CD226⁺CD8⁺IFN-γ⁺T cells/CD8⁺CD226⁺T cells in the epithelial cell region, and CD226⁺CD8⁺IFN-γ⁺T cells/CD8⁺CD226⁺T cells in the stromal cell region in tumor and clinical features of GC patients.

Clinical parameters	cases	CD8⁺CD226⁺IFN-γ⁺T cells among CD8⁺CD226⁺T cells		OR	χ ²	P-value	CD8⁺CD226⁺IFN-γ⁺T cells among CD8⁺CD226⁺T cells		OR	χ ²	P-value	CD8⁺CD226⁺IFN-γ⁺T cells among CD8⁺CD226⁺T cells		OR	χ ²	P-value
Clinical parameters	cases	Low	High	OR	χ ²	P-value	Low	High	OR	χ ²	P-value	Low	High	OR	χ ²	P-value
Gender
Male	64	49	15	1.005	0.0001	0.992	60	4	2.000	0.315	0.574	58	6	0.935	0.077	0.781
Female	34	26	8				30	4				31	3
Age (years)
<66	50	36	14	0.541	1.526	0.217	46	4	0.802	0.013	0.909	45	5	0.857	0.017	0.895
≥66	46	38	8				43	3				42	4
Tumor size (cm)
<5.5	48	38	10	1.411	0.515	0.473	46	2	3.286	1.227	0.268	46	2	3.927	1.962	0.161
≥5.5	48	35	13				42	6				41	7
T stage
T_1-2	15	12	3	1.290	0.001	0.970	14	1	1.307	0.072	0.788	14	1	1.514	0.011	0.917
T_3-4	82	62	20				75	7				74	8
N stage
N₀	27	24	3	2.769	1.664	0.197	26	1	2.889	0.358	0.550	26	1	3.355	0.616	0.433
N_1-3	70	52	18				63	7				62	8
M stage
M₀	89	68	21	0.463	0.077	0.782	82	7	1.673	0.046	0.830	81	8	1.446	0.095	0.758
M₁	8	7	1				7	1				7	1
Pathological stage
II+III	87	70	17	3.431	3.767	0.052	81	6	3.000	0.495	0.482	82	5	9.371	7.611	0.006
IV	11	6	5				9	2				7	4
TNM stage
I+II	41	35	6	2.188	2.196	0.138	40	1	5.833	2.047	0.153	40	1	6.809	2.753	0.097
III+IV	55	40	15				48	7				47	8

The values of cutoff point were 0 (in total region), 0.372 (in epithelial region), 0 (in stromal region). Values higher than the cutoff point were defined as “High”, and others were defined as “Low”. Bold signifies P<0.05.