Table 6.
Uni-variate and multi-variate analysis of clinical parameters of GC patients.
| Clinical parameters | Uni-variate | Multi-variate | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Gender | 1.050 (0.650-1.696) | 0.841 | 0.977 (0.531-1.798) | 0.941 |
| Age (≥66) / (<66) | 1.749 (1.085-2.818) | 0.022 | 1.943 (1.031-3.661) | 0.040 |
| Tumor size (≥5.5) /(<5.5) | 1.764 (1.100-2.828) | 0.018 | 3.956 (1.415-9.140) | 0.007 |
| Pathological stage ((III +IV)/(I+II)) | 2.435 (1.236-4.796) | 0.010 | 0.954 (0.529-1.722) | 0.877 |
| TNM stage ((III +IV)/(I+II)) | 2.504 (1.511-4.149) | 0.000 | 2.829 (1.509-5.301) | 0.001 |
| Frequency of infiltrating PD-L1+Cells in Total (high/low) | 1.501 (0.931-2.419) | 0.095 | 1.001 (0.376-2.671) | 0.997 |
| Frequency of infiltrating PD-L1+CK+Cells (high/low) | 2.134 (1.319-3.452) | 0.002 | 1.191 (0.499-2.838) | 0.693 |
| Frequency of infiltrating PD-L1+Cells in SA Region (high/low) | 1.606 (0.927-2.782) | 0.091 | 1.661 (0.728-3.788) | 0.228 |
| Frequency of infiltrating CD226+Cells in Total (high/low) | 0.554 (0.343-0.894) | 0.016 | 0.492 (0.195-1.244) | 0.134 |
| Frequency of infiltrating CD226+Cells in EP Region (high/low) | 0.528 (0.305-0.914) | 0.023 | 1.018 (0.462-2.245) | 0.964 |
| Frequency of infiltrating CD226+Cells in SA Region (high/low) | 0.641 (0.374-1.098) | 0.105 | 1.295 (0.530-3.165) | 0.571 |
| Frequency of infiltrating CD8+Cells in Total (high/low) | 0.868 (0.541-1.393) | 0.557 | 4.755 (1.342-16.85) | 0.016 |
| Frequency of infiltrating CD8+Cells in EP Region (high/low) | 0.777 (0.480-1.258) | 0.305 | 0.319 (0.094-1.086) | 0.067 |
| Frequency of infiltrating CD8+Cells in SA Region (high/low) | 0.959 (0.597-1.538) | 0.861 | 0.826 (0.329-2.071) | 0.683 |
| Frequency of infiltrating CD8+CD226+Cells in Total (high/low) | 0.563 (0.349-0.907) | 0.018 | 0.612 (0.203-1.849) | 0.384 |
| Frequency of infiltrating CD8+CD226+Cells in EP Region (high/low) | 0.544 (0.323-0.917) | 0.022 | 1.035 (0.436-2.457) | 0.937 |
| Frequency of infiltrating CD8+CD226+Cells in SA Region (high/low) | 0.669 (0.416-1.075) | 0.096 | 0.888 (0.270-2.921) | 0.844 |
Bold signifies P<0.05.