Table 1.
Characteristics of the study population by eGFR category.
| Variables | Before propensity score matching | After propensity score matching | ||||
|---|---|---|---|---|---|---|
| Normal eGFR | Low eGFR | P-value | Normal eGFR | Low eGFR | P-value | |
| n | 39681 | 4256 | 32571 | 4213 | ||
| Age,years | 57.00 ± 9.06 | 60.74 ± 10.08 | <0.001 | 57.92 ± 9.00 | 60.11 ± 10.01 | <0.001 |
| Men,% | 12301(31.0%) | 1128(26.5%) | <0.001 | 10455(32.1%) | 1091(25.9%) | <0.001 |
| BMI,kg/m2 | 24.14 ± 3.66 | 24.67 ± 3.83 | <0.001 | 24.25 ± 3.62 | 24.63 ± 3.80 | <0.001 |
| WC,cm | 85.00(78.00,92.00) | 87.00(80.00,94.00) | <0.001 | 85.00(78.00,92.00) | 87.00(80.00,94.00) | <0.001 |
| SBP,mmHg | 130.00(117.00,144.00) | 140.00(124.00,156.00) | <0.001 | 131.00(118.00,145.00) | 140.00(124.00,156.00) | <0.001 |
| DBP,mmHg | 77.00(70.00,85.00) | 79.00(72.00,88.00) | <0.001 | 77.00(70.00,85.00) | 79.00(72.00,88.00) | <0.001 |
| TC,mmol/L | 4.95(4.21,5.71) | 5.02(4.29,5.77) | 0.006 | 4.98(4.25,5.73) | 5.04(4.31,5.79) | 0.004 |
| TG,mmol/L | 1.32(0.94,1.90) | 1.54(1.08,2.22) | <0.001 | 1.36(0.98,1.93) | 1.56(1.11,2.24) | <0.001 |
| HDL,mmol/L | 1.30(1.09,1.53) | 1.23(1.04,1.46) | <0.001 | 1.31(1.10,1.55) | 1.25(1.06,1.48) | <0.001 |
| LDL,mmol/L | 2.82(2.23,3.43) | 2.92(2.34,3.54) | <0.001 | 2.83(2.24,3.45) | 2.94(2.36,3.56) | <0.001 |
| FBG,mmol/L | 5.50(5.10,6.10) | 5.77(5.20,6.90) | <0.001 | 5.51(5.11,6.12) | 5.77(5.19,6.90) | <0.001 |
| PBG,mmol/L | 7.31(6.00,9.48) | 8.51(6.60,12.20) | <0.001 | 7.30(6.00,9.46) | 8.51(6.59,12.20) | <0.001 |
| HbA1c,% | 5.90 ± 0.30 | 6.10 ± 0.50 | <0.001 | 5.90 ± 0.30 | 6.10 ± 0.50 | <0.001 |
| AST,U/L | 20.00(17.00,24.00) | 21.00(17.00,26.00) | <0.001 | 20.00(17.00,24.00) | 21.00(18.00,26.00) | <0.001 |
| GGT,U/L | 20.00(14.00,31.00) | 22.00(15.00,35.00) | <0.001 | 20.00(14.00,31.00) | 21.00(15.00,35.00) | <0.001 |
| UACR(mg/g) | 8.51(5.38,14.16) | 47.97(36.35,79.18) | <0.001 | 8.56(5.40,14.21) | 47.89(36.31,79.02) | <0.001 |
| BRI | 3.95(3.19,4.81) | 4.32(3.42,5.27) | <0.001 | 3.97(3.20,4.83) | 4.33(3.43,5.29) | <0.001 |
| eGFR,mL/min/1.73m2 | 116.63(105.62,130.14) | 81.60(73.60,86.25) | <0.001 | 115.78(104.32,128.98) | 81.61(73.60,86.26) | <0.001 |
| Smoking habits, % | 0.007 | 0.003 | ||||
| no | 34125(86.0%) | 3579(84.1%) | 28076(86.2%) | 3551(84.3%) | ||
| occasionally | 913(2.3%) | 85(2.0%) | 717(2.2%) | 89(2.1%) | ||
| usually | 4643(11.7%) | 592(13.9%) | 3778(11.6%) | 573(13.6%) | ||
| Current drinker(%) | <0.001 | <0.001 | ||||
| no | 29880(75.3%) | 3170(74.5%) | 24591(75.5%) | 3143(74.6%) | ||
| occasionally | 7222(18.2%) | 796(18.7%) | 5830(17.9%) | 775(18.4%) | ||
| usually | 2579(6.5%) | 290(6.8%) | 2150(6.6%) | 295(7.0%) | ||
| Previous DM (%) | 4206(10.6%) | 775(18.2%) | <0.001 | 3485(10.7%) | 728(18.1%) | <0.001 |
| Previous CHD(%) | 2380(6.0%) | 272(6.4%) | <0.001 | 1987(6.1%) | 270(6.4%) | <0.001 |
Data expressed as mean ± SD for continuous variables or median (IQR) for skewed variables and percentage (%) for categorical variables.
BMI, body mass index; WC, waist circumstance; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; FBG, fasting blood glucose; PBG, 2-h postload blood glucose; HbA1c, glycosylated hemoglobin; AST, aspartate transferase; GGT, gamma-glutamyl transferase; UACR, urinary albumin-creatinine ratio; BRI, body roundness index; eGFR, estimated glomerular fifiltration rate; DM, diabetes mellitus; CHD, coronary heart disease.