Figure 1.

Schematic guidelines for Schaaf-Yang syndrome clinical management.AEDs, anti epileptic drugs; ASD, autism spectrum disorder; CC, corpus callosum; EEG, electroencephalogram; EMG/NCV, electromyogram/nerve conduction velocity; GH, growth hormone; NICU, neonatal intensive care unit; PSG, polysomnography. Perinatal period: Boxes include the medical area of disease. Medical problems and management requirements are detailed below. Childhood and adolescence: Boxes include medical area of disease. Medical problems and diagnosis are detailed below in bold. Management recommendations and complementary examinations are below, not in bold letters with lighter colours at the bottom. Numbers in black dots state the recommended periodicity for clinical evaluation in months for every specialty for all the individuals. In contrast, a P in a red dot means that those complementary examinations and management tools need to be personalised, and applied only if patient’s personal characteristics require them, always following the medical team criteria. For instance, MRI and cardiology are recommended at diagnosis/birth for all patients, but follow-up depends on comorbidities. Please see online supplemental table 2 for more details. A Spanish version of this figure is included as online supplemental figure 1.