Table 3.
Belgium | Canada | Germany* | Israel | Italy | Norway | Portugal | Spain | Sweden | UK | Pooled event rates (95% CI) |
Tau | |
Cardiorenal disease | n/a | 4735 (21.9) | 10 974 (18.6) | 1243 (13.3) | 14 017 (23.5) | 7848 (11.8) | 128 (13.3) | 8846 (48.8) | 14 106 (8.8) | 8750 (13.1) | 19.3 (11.3 to 27.2) | 12.09 |
Heart failure | 256 (19.7) | 2918 (13.5) | 9722 (16.6) | 770 (8.2) | 9987 (16.1) | 6343 (9.5) | 107 (11.1) | 6512 (37.2) | 12 271 (7.6) | 6869 (10.2) | 15.0 (9.5 to 20.4) | 8.75 |
Chronic kidney disease | 251 (19.1) | 1817 (8.4) | 1280 (2.2) | 482 (5.2) | 1531 (2.3) | 1996 (2.9) | 38 (4.0) | 2334 (11.5) | 2425 (1.5) | 2644 (3.8) | 6.0 (2.7 to 9.4) | 5.40 |
Myocardial infarction | 113 (8.1) | 517 (2.4) | 652 (1.1) | 67 (0.7) | 1401 (2.1) | 1541 (2.3) | 21 (2.2) | 1060 (5.0) | 2289 (1.4) | 1320 (1.9) | 2.7 (1.4 to 3.9) | 2.06 |
Stroke | 45 (3.1) | 375 (1.7) | 579 (1.0) | 56 (0.6) | 1699 (2.6) | 282 (0.4) | 18 (1.9) | 765 (3.6) | 2784 (1.7) | 1368 (2.0) | 1.8 (1.2 to 2.4) | 1.02 |
Peripheral artery disease | 51 (3.5) | 284 (1.3) | 1619 (2.8) | 65 (0.7) | 846 (1.3) | 933 (1.4) | 1 (0.1) | 445 (2.1) | 1331 (0.8) | 451 (0.6) | 1.4 (0.8 to 2.0) | 0.98 |
All cause death | 172 (10.7) | 2649 (12.1) | n/a | 1115 (11.9) | n/a | 7920 (11.6) | 114 (11.9) | 2677 (13.1) | 21 966 (13.2) | 13 869 (19.9) | 13.1 (11.1 to 15.1) | 2.89 |
Values are number of events (event rate per 100 patient years).
Random effect estimates were used to calculate pooled values, and tau describes the estimated SD of the underlying data across countries. High heart failure event rates in Spain is partly explained by physicians being prone to admit a patient earlier instead of ambulatory outpatient clinic follow-up.
*Patients identified following a first hospitalisation for heart failure in a specified time period in Germany and Switzerland due to data availability, during 2019 and 2015–2019, respectively.
†Countries with inhospital mortality death only.
n/a, not available.