Adipose tissue and skin gene expression changes across aging. Gene expression by qPCR in axillary scWAT from male BL6 mice (a). Gene expression in axillary scWAT of HET3, males (b) and females (c). Gene expression in axillary scWAT of HET3 in males (b) and females (c). Gene expression of HET3 flank skin in males (d) and females (e). Genes organized into functionally similar groups: vasculature (VA), cytokines (CK), Schwann cell (SC), synaptic (SY), cellular respiration (CR), and collagen (CO). BL6 mice; N = 6–7. HET3 mice; N = 5–7. Unpaired two‐tailed Student's t‐test (a). Kruskal–Wallis nonparametric test with Dunn's post hoc for multiple comparisons, corrected p‐values reported (b–d). Error bars are SEMs. n.s.
p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. a = 30 weeks:60 weeks, b = 30 weeks:126 weeks