Table 1.
Clinicopathological characteristic of circRBM33/FMR1 in prostate cancer (TMA)
| N | circRBM33 expression | χ2 | p value | N | FMR1 expression | p value | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | low | high | (Mean ± SD) | ||||||||
| Type | Normal | 10 | 9 | 1 | 4.102 | 0.043a | 10 | 3.500 ± 1.958 | 0.000c | ||
| Cancerous | 47 | 23 | 24 | 46 | 6.152 ± 0.842 | ||||||
| Gleason score | >7 | 16* | 4 | 12 | 6.751 | 0.034b | 16# | 6.375 ± 0.806 | 0.001d | ||
| =7 | 21 | 11 | 10 | 21 | 6.095 ± 0.768 | ||||||
| <7 | 9 | 7 | 2 | 9 | 5.111 ± 0.782 | ||||||
| Age | <65 | 13 | 8 | 5 | 1.142 | 0.285b | 34 | 5.941 ± 0.952 | 0.648c | ||
| ≥65 | 34 | 15 | 19 | 13 | 6.077 ± 0.760 | ||||||
The expression of circRBM33 was determined by FISH: a represented p value was tested by chi-squared (χ2) test with Yates's correction for continuity; b represented p value was tested by Pearson's χ2 test. The expression of FMR1 was determined by IHC: c represented p value was tested by Student's t test; d represented p value was tested by One-way ANOVA test. * means the expression difference of circRBM33 between GS>7 and GS<7 was statistically different; # means the expression difference of FMR1 between GS>7 and GS<7 was statistically different.