Table 2. Univariable Cox regression analysis for overall survival in luminal A breast cancer patients.
| Variables | Luminal A breast cancer patients (n=226) | ||
|---|---|---|---|
| HR | 95% CI | P value | |
| Age at diagnosis (≥50 vs. <50 years) | 1.252 | 0.926–1.693 | 0.144 |
| Neoadjuvant (yes vs. no) | 1.192 | 0.509–2.790 | 0.686 |
| Vascular tumor thrombus (yes vs. no) | 1.794 | 0.746–4.313 | 0.192 |
| G-CSF (yes vs. no) | 1.107 | 0.465–2.638 | 0.818 |
| T stage (T3–T4 vs. T1–T2) | 3.004 | 1.065–8.475 | 0.038 |
| N stage (N1–N3 vs. N0) | 1.178 | 0.855–1.623 | 0.315 |
| Histology grade (II–III vs. I) | 1.676 | 1.007–2.791 | 0.047 |
| ER status | 0.999 | 0.983–1.014 | 0.848 |
| PR status | 0.996 | 0.981–1.012 | 0.642 |
| NLR (≥2 vs. <2) | 33.26 | 16.98–65.15 | <0.0001 |
HR, hazard ratio; CI, confidence interval; G-CSF, granulocyte colony stimulating factor; ER, estrogen receptor; PR, progesterone receptor; NLR, neutrophil-to-lymphocyte ratio.