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. 2023 Mar 15;15(3):1807–1819.

Figure 2.

Figure 2

Effect of metformin on the phosphorylation levels of STATs in decidual immune cells collected during early pregnancy. A. Representative flow cytometry analysis of pSTAT3+ CD4+ T cells in each group. B. Metformin reduced the ratio of pSTAT3+/CD4+ T cells in normal and inflammatory environments. C. Representative flow cytometry analysis of pSTAT5+/CD4+ T cells in each group. D. Metformin increased the ratio of pSTAT5+/CD4+ T cells in both normal and inflammatory environments. Comparisons among multiple groups were conducted by one-way ANOVA. *P < 0.05; **P < 0.01; ***P < 0.001.