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Classification and characteristics of human monocytes
| Subset | CMs | IMs | NCMs |
|---|---|---|---|
| Markers | CD14++CD16- | CD14+CD16+ | CD14-CD16++ |
| Chemokine receptors | CCR2hi | CCR2hi | CCR2hi |
| CX3CR1lo | CX3CR1hi | CX3CR1lo | |
| HLA-DR + | HLA-DR +++ | HLA-DR ++ | |
| Function | Phagocytosis | Phagocytosis and inflammatory | Patrol |
Notes: Classical monocytes (CMs); Intermediate monocytes (IMs); Non-classical monocytes (NCMs); Chemokine (C-C motor) receptor 2 (CCR2); Chemokine (C-X3-C motor) receptor 1 (CX3CR1).
