Fig. 8.

Investigation of the in vivo therapeutic efficacy of GO/Ga nanocomposites on implant-related bone infection. (a) Schematic description of the in vivo experimental procedures in SD rats (Created with BioRender.com). (b) Systematic evaluation of a microCT-based radiographic analysis of infection-associated osteolysis and bone-implant integration. (c) Morphometric data (BV/TV, BMD and cortical bone porosity) of reconstructed sections in selected ROIs (red rectangle) from harvested femoral shafts. (d) Morphometric data (BV/TV, BMD, Tb. Th and Tb. Sp) of reconstructed sections in selected ROIs (green rectangle) from harvested femoral condyles. Yellow dotted circles represent implants. TR, titanium rods. *p < 0.01 and ^##p < 0.05 compared with the other groups, **p < 0.05 compared with Group UGG, ^#p < 0.05 compared with Groups U and UGG.