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. 2023 Apr 10;6(6):e202302054. doi: 10.26508/lsa.202302054

Figure S3. Evolutionary conservation of vtRNA.

Figure S3.

(A) Vault RNA sequence alignment showing a high sequence similarity. (B) Conservation analysis of vtRNA1-2. The x-axis shows the sequence of vtRNA1-2, and the y-axis shows the conservation scores calculated from the phastCons multiple alignments of 100 vertebrate species. (C) IGV tracks showing coverage plots for mouse vault RNA gene (Vaultrc5) from different tissues (brain, heart, intestine, liver, muscle, pancreas, and spleen) in duplicates/triplicates. The tissues are colour-coded, and the expression is shown as RPM in the top left corner. The black rectangles at the bottom display the length of the gene, and the white arrows represent the strand identity. The framed sequence shows the identified 3′ end fragment of Vaultrc5.