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. 2023 Apr 10;6(6):e202302054. doi: 10.26508/lsa.202302054

Figure S4. vtRNA1-2 associates with Argonaute Proteins.

Figure S4.

(A) IGV tracks of AGO1-4 PAR-CLIP, AGO2/3 RIP-seq, Dicer PAR-CLIP, and small RNA-seq in Dicer KD and WT conditions. Data values are shown in the top left corner. miR-21 is used as a positive control. The bottom line indicates the length of the transcript. (B) IGV tracks showing reads mapping to vtRNA in nuclear and cytoplasmic AGO2 PAR-CLIP data. The bottom black line indicates the length of the transcript, and the sequence below represents the interacting fragment. The top chromosome ideogram shows the position of each gene. miR-21 acts as a positive control for AGO2 binding. (C) svtRNA and miR-5587 sequence alignments show bases with high sequence similarity.