Neurogenic and angiogenic differentiation of BMSCs cultured on various scaffolds. (A) A schematic showing the experimental process of RT-PCR to evaluate the neurogenic and angiogenic differentiation of BMSCs. (B–D) Effect of scaffolds on the neurogenic gene expression of BMSCs, including nestin (B), TUBB3 (C), and NEFL (D). (E, F) Effect of scaffolds on the angiogenic gene expression of BMSCs, including Ang-1 (E) and VEGF (F). *P < 0.05, significant, **P < 0.01 and ***P < 0.001, highly significant (n = 3).