Fig. 4.

Angiogenesis tested for various scaffolds using CAM assay. (A) A schematic showing the experimental process of the CAM test to visualize the angiogenesis with the stimulation directly from scaffolds or their extracts. (B, C) Representative images of blood vessel formation in the CAM test with the presence of scaffolds (B) and scaffold extracts being injected (C). (D–F) Quantification of total tubular length, vessel size, and junction numbers based on panel (C). *P < 0.05, significant, **P < 0.01 and ***P < 0.001, highly significant (n = 3).