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. 2022 Sep 8;290(2):482–501. doi: 10.1111/febs.16604

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© 2022 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Fig. 6 — Comparison of the structure of PaNADK and LmNADK. In all panels, PaNADK and LmNADK structures are shown in green and purple, respectively. (A, B) Superimposed tetrameric form of PaNADK (PDB ID 7QVS) and LmNADK (PDB ID 2I2A) in two different orientations. (C) Superimposed monomeric form of PaNADK and LmNADK highlighting the main structural differences between the two structures, corresponding to extensions or insertions indicated on the sequence alignment (Fig. 5). (D, E) Electron density corresponding to the NADP⁺ bound to PaNADK. The 2F _o − F _c omit map (blue) at a sigma level of 3 is shown in two different orientations. Images of the structures were generated using pymol version 2.5.2, Molecular Graphics System, Schrödinger, LLC. The electron density was generated using ccp4mg‐2.10.11 software.