TABLE 2.

Neutrophils in allergic diseases

Condition	Numbers	Involvement in pathology	Outcome	Reference
Atopic dermatitis	Normal in blood, low in skin	Impaired migration, phagocytosis, and NET formation, increased ROS production	Increased susceptibility to cutaneous infections	88, 90, 108
Allergic rhinitis	Elevated in sputum in severe patients	Not described in detail, however, in neutrophilic endotypes, increased cytokine production, enhanced inflammation	Not described in detail, however, possible contribution to sustained inflammation and tissue damage	95
Eosinophilic asthma	Scarcity of neutrophils in lungs and bronchoalveolar lavage	Unknown	Unknown	90, 109, 110
Neutrophilic asthma	Increased in sputum and airways	Increased propensity for NETs, ROS, and cellular survival	Neutrophilic inflammation	93, 94, 110
Food allergy	Unknown	Unclear, possible activation by IgG instead of IgE, produce platelet‐activating factor	Can induce IgG‐mediated anaphylaxis	111