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. 2022 Sep 16;98(2):238–248. doi: 10.1111/cen.14812

Table 3.

Perceptions of the relative importance of eight potential causes of symptoms of hypothyroidism persisting despite LT4 treatment returning serum TSH to the reference interval

Possible cause Sum of “Strongly agree” + “Agree” (n) Sum of top 3 ranks (n)
Psychosocial factors 134 166
Comorbidities 123 130
Patient unrealistic expectation 113 129
Burden of chronic disease 93 62
Chronic fatigue syndrome 69 61
Inability of levothyroxine to restore normal physiology 39 58
Presence of underlying inflammation due to autoimmunity 38 44
Burden of having to take medication 27 40