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. 2022 Sep 29;38(1):90–100. doi: 10.1002/tox.23664

FIGURE 1.

FIGURE 1

Effect of temozolomide (TMZ) and thymoquinone (TQ) treatment on human glioblastoma cell lines. The viabilities of Hs683, M059J, U251, and U251R 24 h after (A) TMZ treatment. Results revealed that the U251 cell line is very sensitive to TMZ. The viabilities of Hs683, M059J, U251, and U251R 24 h after (B) TQ treatment. All cell lines were more sensitive to TQ than to TMZ. (C) The viabilities of Hs683 and M059J cells 72 h after TQ treatment (10 μM). (D) The viabilities of U251 and U251R cells 72 h after TQ treatment (40 μM). (*p < .05, **p < .01, ***p < .001, compared with U251 control cells; #p < .05, ##p < .01, ###p < .001, compared with U251R control cells)