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. 2023 Apr 10;21:252. doi: 10.1186/s12967-023-04072-z

Table 2.

Association of MetS components, their number, andMetS definition with periodontal health status across strata by sex and smoking habits

Smoke Sex Periodontal status Variables n OR (95% C.I.) p value
Smokers Male Periodontitis (ref. No periodontitis)  ≥ 1MetS factor 694 1.06 (0.78–1.45) 0.717
MetS diagnosis 694 1.05 (0.7–1.58) 0.815
Increased WC 694 1.09 (0.74–1.6) 0.658
High TG 694 0.91 (0.64–1.29) 0.607
Low HDL 694 0.86 (0.59–1.24) 0.423
High BP 694 1.62 (1.11–2.37) 0.012
High glucose 694 1.13 (0.77–1.66) 0.545
No. of MetS factors 694 1.04 (0.93–1.16) 0.53

Bleeding gums

(ref. No bleeding gums)

 ≥ 1MetS factor 694 1.2 (0.87–1.65) 0.271
MetS diagnosis 694 1 (0.65–1.52) 0.987
Increased WC 694 0.95 (0.64–1.41) 0.803
High TG 694 1.14 (0.8–1.63) 0.454
Low HDL 694 0.89 (0.61–1.3) 0.562
High BP 694 1.44 (0.98–2.11) 0.067
High glucose 694 1.06 (0.71–1.57) 0.778
No. of MetS factors 694 1.04 (0.92–1.16) 0.54
Female

Periodontitis

(ref. No periodontitis)

 ≥ 1MetS factor 463 1.7 (1.03–2.83) 0.039
MetS diagnosis 463 1.87 (1.03–3.41) 0.041
Increased WC 463 1.6 (0.97–2.64) 0.068
High TG 463 1.57 (0.85–2.93) 0.151
Low HDL 463 1.31 (0.77–2.21) 0.316
High BP 463 1.39 (0.73–2.65) 0.319
High glucose 463 2.36 (1.24–4.48) 0.009
No. of MetS factors 463 1.21 (1.03–1.44) 0.024

Bleeding gums

(ref. No bleeding gums)

 ≥ 1MetS factor 463 3.04 (1.87–4.93)  < 0.001
MetS diagnosis 463 2.25 (1.3–3.88) 0.004
Increased WC 463 2.88 (1.82–4.55)  < 0.001
High TG 463 1.67 (0.95–2.94) 0.076
Low HDL 463 2.84 (1.79–4.52)  < 0.001
High BP 463 2.16 (1.23–3.79) 0.007
High glucose 463 1.97 (1.07–3.63) 0.03
No. of MetS factors 463 1.45 (1.24–1.69)  < 0.001
Non-smokers Male

Periodontitis

(ref. No periodontitis)

 ≥ 1MetS factor 416 0.82 (0.49–1.35) 0.434
MetS diagnosis 416 1.09 (0.56–2.12) 0.793
Increased WC 416 0.89 (0.47–1.68) 0.712
High TG 416 1.04 (0.56–1.95) 0.901
Low HDL 416 1.1 (0.61–1.97) 0.759
High BP 416 1.03 (0.56–1.89) 0.928
High glucose 416 1.02 (0.55–1.91) 0.948
No. of MetS factors 416 1.01 (0.84–1.2) 0.947

Bleeding gums

(ref. No bleeding gums)

 ≥ 1MetS factor 416 1.05 (0.7–1.57) 0.801
MetS diagnosis 416 1.46 (0.86–2.48) 0.166
Increased WC 416 1.09 (0.66–1.79) 0.745
High TG 416 1.51 (0.92–2.49) 0.101
Low HDL 416 1.32 (0.82–2.12) 0.25
High BP 416 1.08 (0.66–1.76) 0.762
High glucose 416 1.14 (0.69–1.88) 0.608
No. of MetS factors 416 1.09 (0.94–1.25) 0.254
Female

Periodontitis

(ref. No periodontitis)

 ≥ 1MetS factor 685 1.58 (0.99–2.53) 0.056
MetS diagnosis 685 1.86 (1.07–3.24) 0.027
Increased WC 685 2 (1.26–3.18) 0.003
High TG 685 1.68 (0.91–3.09) 0.098
Low HDL 685 0.84 (0.48–1.47) 0.543
High BP 685 1.63 (0.93–2.85) 0.085
High glucose 685 2.02 (1.16–3.52) 0.013
No. of MetS factors 685 1.22 (1.04–1.43) 0.015

Bleeding gums

(ref. No bleeding gums)

 ≥ 1MetS factor 685 1.96 (1.4–2.76)  < 0.001
MetS diagnosis 685 1.63 (1.06–2.51) 0.026
Increased WC 685 2.07 (1.47–2.91)  < 0.001
High TG 685 1.64 (1.02–2.63) 0.041
Low HDL 685 1.56 (1.07–2.27) 0.019
High BP 685 1.39 (0.9–2.14) 0.137
High glucose 685 1.72 (1.11–2.67) 0.015
No. of MetS factors 685 1.27 (1.12–1.43)  < 0.001