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. Author manuscript; available in PMC: 2023 Apr 11.
Published in final edited form as: Mol Pharm. 2019 Dec 31;17(2):404–416. doi: 10.1021/acs.molpharmaceut.9b00644

Figure 3.

Figure 3.

Effects of BDNF (5.71 nmol/kg) + ADTC5 (10 μmol/kg), BDNF alone (5.71 nmol/kg), or vehicle treatments in the presence of NG2 receptor in the medial corpus callosum of brains of SJL/elite EAE mice as stained by DAB. (A) Color photomicrograph of anti-NG2 staining (brown) taken under identical conditions from the medial corpus callosum for mice treated with BDNF + ADTC5, BDNF alone, vehicle; the red arrows point to dense regions of activated NG2-glia. (B) Quantitative NG2 density comparison among the EAE mice treated with BDNF + ADTC5, BDNF alone, and vehicle; scale bar = 50 μm; **p ≤ 0.01; one-way ANOVA (95% confidence; n = 5).