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. 2023 Mar 28;14:1115399. doi: 10.3389/fpsyt.2023.1115399

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Copyright © 2023 Smith, Sershen, Youssef, Lajtha, Jin, Zhang, Chen, Guidotti and Davis.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Graphical Representation of Mediation Effects of MATRICS Speed of Processing Score on Odor Identification (A) and Odor Discrimination (B). Each number is the β value from the mediation analysis of either the direct effect (ADE) of diagnostic group (schizophrenia vs. control) on odor variables controlling for the mediator and covariates (age, sex and number of cigarettes smoked) (bottom arrow), or the indirect mediation effect (ACME) (the product of the two side arrows), Statistical significance of β value: * p < 0.05,** p < 0.01, ***p < 0.001.