Table 1.
Characteristics of subjects.
| Characteristic | Schizophrenia–CSZ | Controls | Test |
|---|---|---|---|
| (n = 58) | (n = 48) | ||
| Age (m) | 44.7 ± 9.6 | 35.6 ± 10.9 | T = 4.57, df = 104, p = <0.001 |
| Sex (M/F) (n) | 50/8 | 32/16 | Χ2 = 5.73, df = 1 p = 0.017 |
| Race (W/B/H/A) (n) | 16/37/3/2 | 13/31/2/2 | FET = 1.000 |
| Cigarette smoker (Y/N) (n) | 36/22 | 9/39 | Χ2 = 20.17df = 1, p < 0.001 |
| Cigarette smoked/wk. (m) | 36.2 ± 45.0 | 11.8 ± 27.8 | T = 3.26, df = 104, p = 0.001 |
| Handedness (right/left) | 54/4 | 45/3 | Χ2 = 0.02, df = 1, p = 0.89 |
| Antipsychotic treatment (lst Gen/2nd Gen/combined (n) | 4/36/18 | NR | |
| On Clozapine (Y/N) (n) | 27/31 | NR | |
| On Antidepressant (Y/N/) (n) | 6/52 | 0/48 | |
| On Mood stabilizer (Y/N) (n) | 23/35 | 0/48 | |
| On Valproate (Y/N) (n) | 9/49 | 0/48 | |
| On Benzodiazepine (Y/N) (n) | 22/38 | 0/48 | |
| PANSS total (m) | 71.6 ± 15.1 | NR | |
| MATRICS overall composite (m) | 21.45 ± 12.57 | 41.53 ± 9.76 | F = 8.89, df = 100, p < 0.001 |
| Urine Tox THC (P/N) (n) | 0/24 | 4/32 | FET = 0.13 |
NR, not relevant; (n), number of subjects; m, Mean ± S.D.; (Y/N), Yes/No; (P/N), Positive/Negative; (M/F), male/female, Race/Ethnicity: W, Caucasian; B, Black or African American; H, Hispanic; A, Asian. Antipsychotic type: lst Generation antipsychotic, 2nd generation antipsychotic, combined lst and 2nd Generation antipsychotic. Statistical tests: Χ2, chi-square; FET, Fishers’ exact test; T, t-test. We did not collect data on education level of our subjects. Cigarettes smoked per week is the subject’s response estimate of how many cigarettes they have smoked per week in the last few weeks.