Table 6.
Correlations between odor identification or odor discrimination scores and cognitive measures and interaction effects between sex and cognitive measures in subjects with Chronic Schizophrenia (CSZ).
| Odor identification | Odor discrimination | |||||
|---|---|---|---|---|---|---|
| MATRICS cognitive measure | Correlation male CSZ (n = 48–49) | Correlation female CSZ (n = 7–8) | Interactions with sexa | Correlation male CSZ (n = 48–49) | Correlation female CSZ (n = 7–8) | Interactions with sexa |
| Speed of processing | r = 0.301 p = 0.036 | r = 0.600 p = 0.116 | F = 1.09 p = 0.301 | r = 0.194 p = 0.181 | r = 0.561 p = 0.148 | F = 1.22 p = 0.275 |
| Attention Vigilance | r = 0.119 p = 0.420 | r = 0.573 p = 0.178 | F = 1.37 p = 0.247 | r = 0.141 p = 0.340 | r = 0.667 p = 0.102 | F = 1.74 p = 0.193 |
| Working Memory | r = 0.171 p = 0.239 | r = 0.692 p = 0.057 | F = 1.54 p = 0.220 | r = 0.245 p = 0.089 | r = 0.840 p = 0.009 | F = 1.96 p = 0.167 |
| Verbal Learning | r = 0.094 p = 0.521 | r = 0.431 p = 0.286 | F = 0.85 p = 0.362 | r = 0.249 p = 0.085 | r = 0.759 p = 0.029 | F = 2.20 p = 0.144 |
| Visual Learning | r = 0.094 p = 0.521 | r = 0.324 p = 0.434 | F = 0.36 p = 0.548 | r = 0.039 p = 0.788 | r = 0.838 p = 0.009 | F = 4.25 p = 0.044 |
| Reasoning/Problem Solving | r = 0.264 p = 0.067 | r = 0.338 p = 0.413 | F = 0.10 p = 0.751 | r = 0.135 p = 0.355 | r = −0.011 p = 0.980 | F = 0.10 p = 0.751 |
| Social cognition | r = −0.060 p = 0.687 | r = 0.321 p = 0.439 | F = 0.92 p = 0.343 | r = −0.054 p = 0.714 | r = 0.796 p = 0.018 | F = 4.63 p = 0.036 |
| Overall composite score | r = 0.212 p = 0.149 | r = 0.704 p = 0.078 | F = 1.59 p = 0.213 | r = 0.222 p = 0.129 | r = 0.931 p = 0.002 | F = 3.24 p = 0.078 |
r = Pearson correlation coefficient. aRepresents the significance of additional effect of sex on the correlation with the cognitive variable in females compared to the cognitive variable in males. Statistic derived from multiple regression analysis to assess the sex effect in schizophrenia patients. Bolded values are statistically significant F at P< 0.05.