Table 1.

Demographic, PN phenotype, and clinical characteristics of 13 GFAP-IgG-positive patients.

Pt. no.	Age (y) / sex	Pattern of PN	Symptoms of autonomic and cranial neuropathy	CNS syndromes	Electrodiagnostic studies			Brain or spinal lesions	Nerve root enhancement	Treatment	Max. mRS/last follow-up mRS
					Axonal neuropathy	Demyelinating neuropathy	Abnormal F or H reflexes
1	29/M	Sensorimotor axonal neuropathy	Tachycardia, abdominal distension	Meningoencephalomyelitis	Yes	No	Yes	Yes	No	Steroids, IVIG	5/3
2	55/M	Sensorimotor axonal and demyelinating neuropathy	Abdominal distension	Encephalomyelitis	Yes	Yes	No	No	Yes	Steroids, IVIG	4/2
3	54/M	Predominant motor axonal neuropathy	Bradycardia	Meningoencephalomyelitis	Yes	No	Yes	Yes	NA	Steroids, IVIG, PE	5/4
4	59/M	Predominant motor axonal neuropathy	None	Meningoencephalomyelitis	Yes	No	Yes	Yes	NA	Steroids, IVIG	4/4
5	43/M	Predominant motor axonal neuropathy	Orthostatic hypotension, abdominal distension	Meningoencephalomyelitis	Yes	No	Yes	Yes	Yes	Steroids, IVIG	5/4
6	29/F	Predominant motor axonal neuropathy	Hyperhidrosis, diplopia	Meningoencephalitis	Yes	No	Yes	No	NA	Steroids	3/1
7	47/F	Predominant motor axonal neuropathy	None	Encephalitis	Yes	No	No	Yes	NA	Steroids	2/1
8	68/M	Motor axonal neuropathy	Abdominal distension	Meningoencephalomyelitis	Yes	No	No	Yes	NA	Steroids	5/2
9	48/M	Motor axonal neuropathy	Constipation, diarrhea, abdominal distension, hyperhidrosis	Meningomyelitis	Yes	No	Yes	No	Yes	Steroids	4/1
10	35/M	Motor axonal neuropathy	None	Meningoencephalomyelitis	Yes	No	No	No	Yes	Steroids, IVIG	3/1
11	36/F	Sensorimotor neuropathy	Abdominal distension	Encephalomyelitis	No	No	Yes	No	Yes	Steroids	4/3
12	30/F	Sensorimotor neuropathy	Abdominal distension	Meningoencephalomyelitis	No	No	Yes	Yes	No	Steroids, IVIG	3/0
13	30/M	Sensorimotor neuropathy	Diplopia	Meningomyelitis	No	No	No	Yes	NA	Steroids	2/0

CNS, central nervous system; F, female; IVIG, intravenous immunoglobulins; M, male; Max., maximum; mRS, modified Rankin scale; NA, not available; PE, plasma exchange; PN, peripheral neuropathy; Pt., patient; y, years.