Table 1.
Demographic and clinical characteristics by frailty status among people with HIV in clinical care at 7 sites across the United States, 2016-2019 (n=9,336)
| Characteristic a | Overall b (n=9,336) 100% n (%) |
Not frail c (n=4,033) 43% n (%) |
Prefrail c (n=4,092) 44% n (%) |
Frail c (n=1,211) 13% n (%) |
p-value |
|---|---|---|---|---|---|
| Sex | |||||
| Female | 1,393 (15) | 494 (35) | 660 (47) | 239 (17) | <0.001 |
| Male | 7,943 (85) | 3,539 (45) | 3,432 (43) | 972 (12) | |
| Age | <0.001 | ||||
| <30 | 482 (5) | 249 (52) | 215 (45) | 18 (4) | |
| 30-39 | 1,740 (19) | 865 (50) | 739 (42) | 136 (8) | |
| 40-49 | 2,147 (23) | 942 (44) | 937 (44) | 268 (12) | |
| 50-59 | 3,301 (35) | 1,337 (41) | 1,431 (43) | 533 (16) | |
| ≥60 | 1,666 (18) | 640 (38) | 770 (46) | 256 (15) | |
| Race/ethnicity | <0.001 | ||||
| White | 4,507 (48) | 1,836 (41) | 2,041 (45) | 630 (14) | |
| Black | 2,860 (31) | 1,306 (46) | 1,229 (43) | 325 (11) | |
| Hispanic | 1,458 (16) | 669 (46) | 603 (41) | 186 (13) | |
| Other | 511 (5) | 222 (43) | 219 (43) | 70 (14) | |
| HIV transmission risk factor | <0.001 | ||||
| MSM | 5,973 (64) | 2,718 (45) | 2,551 (43) | 704 (12) | |
| Heterosexual | 2,005 (21) | 862 (43) | 865 (43) | 278 (14) | |
| IDU | 1,074 (12) | 345 (32) | 533 (50) | 196 (18) | |
| Other | 284 (3) | 108 (38) | 143 (50) | 33 (12) | |
| Nadir (lowest) CD4 count (cells/mm3) | 0.24 | ||||
| <350 | 6,143 (66) | 2,633 (43) | 2,686 (44) | 824 (13) | |
| 350-499 | 1,509 (16) | 681 (45) | 644 (43) | 184 (12) | |
| ≥500 | 1,684 (18) | 719 (43) | 762 (45) | 203 (12) | |
| Current CD4 count (cells/mm3) | <0.001 | ||||
| <350 | 1,586 (17) | 598 (38) | 713 (45) | 275 (17) | |
| 350-499 | 1,532 (16) | 641 (42) | 685 (45) | 206 (13) | |
| ≥500 | 6,218 (67) | 2,794 (45) | 2,694 (43) | 730 (12) | |
| Receiving ART | 8,942 (96) | 3,883 (43) | 3,902 (44) | 1,157 (13) | 0.11 |
| HIV viral load (copies/mL) | <0.001 | ||||
| Detectable (≥200) | 889 (10) | 301 (34) | 406 (46) | 182 (20) | |
| Undetectable (<200) | 8,435 (90) | 3,728 (44) | 3,681 (44) | 1,026 (12) |
ART: antiretroviral therapy; BMI: body mass index; MSM: men who have sex with men; IDU: injection drug use
Not frail: 0 symptoms; Prefrail: 1-2 symptoms; Frail: 3-4 symptoms
a
Data presented as n (%)
b
Column percentage
c
Row percentage